Course Description:

The structure and function of the cell. Physical and chemical properties of water and its importance to the living cells. Structure and function of micro and macromolecules as well as vitamins in the biological systems. The basics of enzymes and hormones.

 Course Syllabus

The course contain 9 chapters as following

• 1-The foundation of biochemistry and properties of life. The main structure, functions and differences of prokaryotes, Eukaryotes and plant cells. The content of the cell: elements small molecules macromolecules and supramolecules.The metabolic process and energy forms.
• 2-2- Water unusual properties and its interaction with hydrophilic and hydrophobic molecules. Non covalent bonding and its importance to macromolecules structure and functions. The equilibrium constant and water ionization and the pH scale. Weak acids and bases characteristic dissociation constants and their titration curves.Cell buffers against pH changes
• 3-Carbohydrates: physical and chemical properties of monosaccharide di- and polysaccharides.Classification, configuration and mutarotation as well as glycosaminoglycan and glycoproteins.
• 4-Lipids and membranes:
• 5-Amino acids structure peptides and protein structures and functions
• 6-Enzyme nomenclature and properties
• 7-Nucleic acids structure and functions
• 8-Structure and functions of water and lipid soluble vitamins
• 9-Introduction to hormones

Main Text book:

الكتاب الأساسى

Voet D. and Voet J. (2005). Biochemistry (3^rd ed.) J. Wiley (USA)

Instructor hand out both available from Al-Shigri and Al- Kwarizmi bookstore, University street

General Text-Books

Bettelheim, F. (2007). Introduction to general, organic, and Biochemistry (8^th ed.). Belmont, Thomson Brooks/Cole. ISBN-13: 978-0-495-01197-2.

Lehninger A. L., Nelson D. L. and Cox M. M. (2004)

Principals of Biochemistry W. H. Freeman & Company, New York.

Devlin T. M. (2002)

Textbook of Biochemistry: With Clinical Correlations.

Wiley-Liss, New York.

Harper’s Biochemistry (2000)

Murray R., Granner D., Mayers P. and Rodwell V. (2000)

McGraw-Hill, New York.

Campbell P, and Smith A. (2000)

Biochemistry Illustrated

Churchill-Livingston, Edinburgh, London.

Champ P, Harvey R, and Ferrier D, Lippincott's Illustrated Reviews: Biochemistry Lippincott Williams & Wilkins 3rd edition (2005).

E-resources:

مصادر المعرفة الاخرى

Biochemistry online by Henry Jacubowski http://employees.csbsju.edu/hjakubowski/classes/ch331/bcintro/default.html

www. Online web sites for biochemistry lecture notes, carrying the suffix “. edu”

Other textbooks might be acceptable. Please check with your instructor.